這是真的嗎？？？？？
研究：養狗有益提昇孩童抗過敏能力
更新日期:2008/04/29 10:50 鄭詩韻
（法新社巴黎二十九日電） 科學家發現，人類最好的朋友對小孩子也有好處，因為與狗一起生活的小孩，免疫系統對抗氣喘等過敏的能力可能提高。
德國慕尼黑海姆霍茲中心流行病學研究所的海恩瑞希，針對三千多名孩童進行調查，密切注意這些孩子從出生到六歲的健康狀況。
血液測試顯示，家裡有養狗的小孩，比較不像家裡沒養狗的小孩，容易對容易對引發氣喘、過敏性鼻炎、濕疹的花粉與吸入性過敏原過敏。
海恩瑞希認為，早期接觸到狗毛帶進屋內的細菌，可刺激免疫系統成熟，換言之，身體的防禦系統突然碰到家居塵蹣、花粉等過敏原時，不會突然手忙腳亂。
但研究發現，奇怪的是，這些在小孩抗體上看到的好處，不太容易從症狀上看出來。
養狗和不養狗家庭的孩子，都容易感染過敏等問題。
海恩瑞希告訴法新社：「原因還不是很清楚。」他說，可能是因為保護上的益處，要到這些參與研究的小孩比較大以後才看得出來。這些孩子十歲時，會接受更進一步的評估。
研究報告發表於歐洲呼吸協會的「歐洲呼吸期刊」。
該文原paper摘要如下：發表於今年5月的Europien Respiratory Journal
Title: Dog ownership and contact during childhood and later allergy development
Corresponder是J. Heinrich，我怕有版權問題，只節錄abstract如下：
ABSTRACT: The effect of dog ownership during childhood on the development of allergy has been investigated in few studies with conflicting results. The association between dog contact and indoor endotoxin exposure during infancy and the development of allergic sensitisation and atopic disease up to age 6 yrs was investigated.
Two ongoing birth cohorts, the German Infant Nutrition Intervention Programme (GINI;n51,962) and the Influences of Lifestyle Related Factors on the Human Immune System and Development of Allergies in Children (LISA; n51,193), were analysed. In both studies, information on children’s contact with dogs and their allergic symptoms and doctor-diagnosed allergic disease were collected during follow-up using questionnaires. Specific immunoglobulin E to common aeroallergens was measured at age 6 yrs. House dust samples were collected at age 3 months and the amount of endotoxin was determined.
Dog ownership in early childhood was associated with a significantly lower rate of mixed pollen and inhalant sensitisation but not with dog sensitisation or allergic symptoms and diseases up to age 6 yrs. Regular contact with dogs, without ownership, during childhood was not associated with those health outcomes. No associations were found between house dust endotoxin exposure during infancy and sensitisation outcomes.
In conclusion, dog ownership in early childhood protects against the development of inhalant sensitisation and this effect cannot be attributed to the simultaneous exposure to endotoxin.
這篇告訴我們幾件事：
1.統計這東西，「
2.對照組是曾摸過狗的6歲以下小孩。
3.未養狗的小孩與狗接觸的時間長短(1歲及四歲)跟過敏與否無關。
4.養狗可以降低你血中的IgE跟花粉及吸入性過敏原起反應的機會，但是沒辦法減輕你過敏或氣喘的症狀。
5.
6.養狗不會增加你對狗過敏的機會(但是該團隊之前有paper說，養貓會增加你對貓過敏的機會)
7.以上結論適用年齡：6歲以下。
8.原來德國的環保局會support這種研究。
這篇報告沒告訴我們的事：
1.養狗的6歲以下小孩(以下的『小孩』都是指6歲以下)跟沒養狗的小孩生活型態有一些不同。至少大部份養狗的得去溜狗，得跟戶外接觸。(那到底是「養狗」造成的「保護你的IgE不跟花粉反應但是不會減緩症狀」，還是「出去溜狗」造成的？)
2.
3.曾有報告說養貓的IgG4會比較高，甚至可以block specific IgE (個人未查證block這部份)，也許這麼多人也可以看一下IgG4
4.不知這群小朋友family size如何，1989年有人說family size會影響atopy...
這篇報告還預告了：
1.他們四年後還有一篇paper，要看這群小孩十歲時的狀況
其他：
媒體不可靠... 還是要靠自己... -_-
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